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... > NATURAL PHENOMENON OR PROCESS > BIOLOGICAL PHENOMENON > genetic processes > gene expression regulation > gene amplification

PREFERRED TERM

gene amplification

TYPE

Topic

DEFINITION

A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the production of an RNA transcript of the entire repeating sequence of ribosomal RNA followed by the reverse transcription of the molecule to produce an additional copy of the original DNA sequence.
Aumento selectivo del número de copias de un gen que codifica una proteína específica sin un aumento proporcional en los otros genes. Se produce en forma natural mediante la extensión de una copia de la secuencia que se repite desde el cromosoma y su replicación extracromosómica es un plasmido, o mediante la producción de una transcripción de ARN de toda la secuencia que se repite de ARN ribosomático, seguido de transcripción inversa de la molécula para producir una copia adicional de la secuencia original de ADN.

BROADER CONCEPT

gene expression regulation

RELATED CONCEPTS

DNA

ALTERNATIVE LABEL

amplification
amplification, gene
DNA amplification
DNA amplification (in vivo)
RNA amplification (in vivo)

SCOPE NOTE

Amplification in vivo; for amplification in vitro use the name of the technique, e.g. 'polymerase chain reaction'.

BELONGS TO GROUP

IN OTHER LANGUAGES

DNA-vermenigvuldiging	Dutch
vermenigvuldiging
amplificação	Portuguese
amplificación genética	Spanish
amplificación

URI

http://id.agrisemantics.org/gacs/C12029

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EXACT MATCH

http://id.cabi.org/cabt/9703	id.cabi.org
http://id.cabi.org/cabt/40155	id.cabi.org
http://lod.nal.usda.gov/nalt/8126	lod.nal.usda.gov